Metformin hcl 500 mg tablet

Are you looking for an effective medication to manage your type 2 diabetes?

Look no further than Metformin HCL 500 mg Tablet.

Metformin HCL is a widely prescribed oral medication that helps regulate blood sugar levels in individuals with type 2 diabetes. Whether you have just been diagnosed or have been managing your diabetes for years, Metformin HCL can be an essential part of your treatment plan.

So, what are the key benefits of using Metformin HCL 500 mg Tablet?

1. Blood Sugar Regulation: Metformin HCL works by reducing glucose production in the liver and enhancing insulin sensitivity in your body. This leads to improved blood sugar control, preventing spikes and keeping your levels stable throughout the day.

2. Weight Management: Many individuals with type 2 diabetes struggle with weight management. Metformin HCL can help with that! It is known to promote modest weight loss, making it an excellent choice for those looking to shed a few pounds.

3. Fewer Side Effects: Unlike some other diabetes medications, Metformin HCL has fewer side effects. Common side effects may include mild gastrointestinal distress, such as nausea or diarrhea, which usually subside over time.

4. Heart Health: Metformin HCL has also been shown to have additional benefits for heart health. It may help reduce the risk of heart disease and improve lipid profiles, promoting a healthy cardiovascular system.

How should you take Metformin HCL 500 mg Tablet?

Your doctor will determine the appropriate dosage for you based on your individual needs. It is typically taken with meals to reduce the risk of stomach upset. Remember to follow your doctor's instructions and maintain a healthy lifestyle, including regular exercise and a balanced diet.

Don't let diabetes control your life any longer. Take control of your health with Metformin HCL 500 mg Tablet. Talk to your doctor today to see if it's the right choice for you.

"Metformin HCL 500 mg Tablet: Your partner in diabetes management."

About Metformin HCL

Metformin HCL is a medication commonly prescribed for the treatment of type 2 diabetes. It belongs to a class of drugs called biguanides, which work by reducing the amount of glucose produced by the liver and improving the body's response to insulin.

This medication is available in the form of tablets and is typically taken orally with meals. The recommended dosage of Metformin HCL varies depending on individual needs and should be determined by a healthcare professional.

Metformin HCL is often used as an initial treatment for type 2 diabetes and can also be used in combination with other antidiabetic medications. It helps to lower blood sugar levels and can improve glycemic control over time.

Like any medication, Metformin HCL may cause side effects in some individuals. Common side effects may include gastrointestinal symptoms such as nausea, vomiting, and diarrhea. These side effects are usually mild and go away on their own.

It is important to follow the prescribed dosage and instructions provided by your healthcare professional when taking Metformin HCL. Regular monitoring of blood sugar levels and regular visits to your healthcare provider are also important for optimal management of diabetes.

If you have any questions or concerns about Metformin HCL or your diabetes treatment, it is best to consult with your healthcare professional for personalized advice and guidance.

What is Metformin HCL?

Metformin HCL, also known as metformin hydrochloride, is a medication commonly prescribed to treat type 2 diabetes. It belongs to a class of drugs called biguanides, which work by decreasing the amount of glucose produced by the liver and increasing the body's sensitivity to insulin.

How does Metformin HCL work?

Metformin HCL works by lowering the blood sugar levels and improving insulin sensitivity in the body. It helps to control glucose production by the liver and increases the uptake of glucose by the cells, thereby lowering blood sugar levels. This mechanism of action helps manage and regulate blood sugar levels in individuals with type 2 diabetes.

What are the uses of Metformin HCL?

Metformin HCL is primarily used to treat type 2 diabetes in adults. It is often prescribed in combination with lifestyle changes, such as diet and exercise, to help control blood sugar levels. It may also be used off-label for other conditions, such as polycystic ovary syndrome (PCOS) and gestational diabetes.

What is the recommended dosage of Metformin HCL?

The recommended dosage of Metformin HCL varies depending on the individual's age, medical condition, and response to treatment. It is typically taken orally 1-3 times a day with meals to help reduce stomach upset. It is important to follow the dosage instructions provided by your doctor and to regularly monitor your blood sugar levels while taking this medication.

What are the possible side effects of Metformin HCL?

Like any medication, Metformin HCL can cause side effects. Common side effects may include nausea, vomiting, diarrhea, stomach upset, and a metallic taste in the mouth. These side effects are usually mild and temporary. However, if you experience severe or persistent side effects, it is important to seek medical attention.

How does Metformin HCL work?

If you have type 2 diabetes, your body doesn't use insulin properly, resulting in high blood sugar levels. Metformin HCL 500 mg tablet works by improving insulin sensitivity and reducing the amount of glucose produced by the liver. This helps to lower blood sugar levels and maintain them within the target range.

When you take Metformin HCL, it decreases the amount of sugar your liver releases into your bloodstream. It also enhances the body's response to insulin, making it more effective in lowering blood sugar levels. This can lead to better control of your diabetes and reduce the risk of complications associated with high blood sugar.

In addition to its effects on blood sugar control, Metformin HCL 500 mg tablet may also promote weight loss in some individuals. It can reduce appetite and help to regulate the body's metabolism, resulting in a caloric deficit and potential weight loss.

Furthermore, Metformin HCL has been shown to have positive effects on cardiovascular health. It can improve lipid profiles by reducing levels of LDL cholesterol and triglycerides, while increasing levels of HDL cholesterol. This can reduce the risk of heart disease and stroke, which are common complications of diabetes.

Overall, Metformin HCL 500 mg tablet is an effective medication for managing type 2 diabetes. It works by improving insulin sensitivity, reducing liver glucose production, promoting weight loss, and improving cardiovascular health. Speak to your doctor to see if Metformin HCL is the right treatment option for you.

Uses of Metformin HCL 500 mg Tablet

1. Treatment of Type 2 Diabetes

Metformin HCL 500 mg Tablet is primarily used for the treatment of type 2 diabetes. It works by lowering the blood sugar levels in the body and improving insulin sensitivity. This medication helps to control and manage diabetes by reducing the production of glucose in the liver and increasing the uptake and utilization of glucose by the cells.

2. Prevention of Diabetes Complications

In addition to managing blood sugar levels, Metformin HCL 500 mg Tablet is also used to prevent various complications associated with diabetes. It helps to reduce the risk of cardiovascular diseases, such as heart attacks and strokes, by improving the overall cardiovascular health. This medication also helps in preventing kidney damage and diabetic neuropathy.

3. Polycystic Ovary Syndrome (PCOS)

Metformin HCL 500 mg Tablet is sometimes prescribed for the treatment of polycystic ovary syndrome (PCOS). It helps in regulating menstrual cycles and improving fertility in women with PCOS. This medication also helps in reducing excessive hair growth, acne, and insulin resistance commonly associated with PCOS.

4. Gestational Diabetes

During pregnancy, some women may develop gestational diabetes, which can potentially harm both the mother and the baby. Metformin HCL 500 mg Tablet may be prescribed to manage gestational diabetes and maintain normal blood sugar levels. This medication helps in reducing the risk of complications during pregnancy and childbirth.

5. Weight Management

In some cases, Metformin HCL 500 mg Tablet may be prescribed to help with weight management. It can aid in weight reduction and prevent weight gain, particularly in individuals with diabetes. This medication helps in controlling appetite, improving metabolism, and facilitating the utilization of glucose for energy production.

Treating type 2 diabetes

Metformin HCL 500 mg Tablet

Metformin HCL 500 mg Tablet is a commonly prescribed medication for the treatment of type 2 diabetes. It works by improving insulin sensitivity and reducing the amount of glucose produced by the liver. This helps to lower blood sugar levels and maintain them within a healthy range. By taking this medication as directed, you can effectively manage your diabetes and prevent complications associated with high blood sugar.

Dosage and Usage

It is important to take Metformin HCL 500 mg Tablet exactly as prescribed by your healthcare provider. The typical dosage for adults is usually one tablet taken with each meal, which can be adjusted based on your individual needs. It is advised to take this medication with food to prevent stomach upset. Your healthcare provider may also recommend lifestyle changes such as a healthy diet and regular exercise to help improve the effectiveness of the medication.

Possible Side Effects

Like all medications, Metformin HCL 500 mg Tablet can potentially cause side effects. These may include nausea, diarrhea, stomach pain, and a metallic taste in the mouth. These side effects are usually temporary and subside with continued use of the medication. However, if you experience severe or persistent side effects, it is important to consult your healthcare provider.

Precautions and Considerations

Prior to starting treatment with Metformin HCL 500 mg Tablet, inform your healthcare provider about any existing medical conditions, allergies, or medications you are currently taking. It is important to mention if you have kidney or liver disease, as these conditions may affect the dosage and safety of this medication. It is also important to monitor your blood sugar levels regularly and stay in regular contact with your healthcare provider to ensure the medication is effectively managing your diabetes.

In summary

Metformin HCL 500 mg Tablet is a widely used medication for the treatment of type 2 diabetes. By taking this medication as directed, along with making lifestyle changes, you can effectively manage your diabetes and reduce the risk of complications. If you have any questions or concerns about this medication, consult with your healthcare provider for personalized advice and guidance.

Managing polycystic ovary syndrome (PCOS)

Understanding PCOS

Polycystic ovary syndrome (PCOS) is a hormonal disorder that affects women of reproductive age. It is characterized by enlarged ovaries with small cysts, irregular or absent menstrual periods, and elevated levels of androgens.

PCOS can cause a range of symptoms, including weight gain, acne, excessive hair growth, and fertility problems. It is important to manage PCOS effectively to minimize these symptoms and reduce the risk of long-term complications.

Treatment options for PCOS

Metformin HCL 500 mg tablet is one of the commonly prescribed medications for managing PCOS. It is an oral medication that helps to improve insulin sensitivity and regulate menstrual cycles.

In addition to medication, lifestyle changes such as maintaining a healthy weight, eating a balanced diet, and exercising regularly can also help in managing PCOS. These changes can help to regulate hormone levels, improve fertility, and reduce the risk of complications associated with PCOS.

The benefits of Metformin HCL 500 mg tablet

Metformin HCL 500 mg tablet can effectively reduce insulin resistance, which is a common feature of PCOS. By improving insulin sensitivity, it helps to regulate menstrual cycles and restore ovulation in women with PCOS.

In addition to its effects on insulin, Metformin HCL 500 mg tablet can also help in weight management and reducing the risk of type 2 diabetes. It has been shown to promote weight loss and improve lipid profiles in women with PCOS.

Furthermore, Metformin HCL 500 mg tablet has been found to have beneficial effects on other symptoms of PCOS, such as acne and excessive hair growth. It can help in reducing these symptoms and improving the overall quality of life for women with PCOS.

Consult your doctor

If you are experiencing symptoms of PCOS or have been diagnosed with the condition, it is important to consult your doctor for appropriate management and treatment. Your doctor can assess your individual needs and help you develop a personalized plan to manage PCOS effectively.

Remember to take any medications as prescribed and make necessary lifestyle changes to support your overall health and well-being. With proper management, PCOS can be effectively controlled, allowing you to lead a healthy and fulfilling life.

Dosage and Administration

Recommended Dosage

The recommended dosage of Metformin HCL 500 mg tablet depends on the individual's medical condition, response to treatment, and other factors. It is important to follow the instructions provided by your healthcare provider or pharmacist. In general, the initial dose for adults is usually 500 mg taken once daily with the evening meal.

Dosage Adjustment

The dosage of Metformin HCL 500 mg tablet can be adjusted based on the individual's blood glucose levels. Regular monitoring of blood glucose levels is important to determine if the dosage needs to be increased or decreased. Your healthcare provider may gradually increase the dosage by 500 mg every 1 to 2 weeks until the desired blood glucose control is achieved.

Administration

Metformin HCL 500 mg tablet should be taken orally with a full glass of water. It is usually taken with meals to reduce the risk of gastrointestinal side effects. Swallow the tablet whole, without chewing or crushing it. If you are taking other medications, it is recommended to take them at least 2 hours before or after taking Metformin HCL 500 mg tablet to avoid any potential interactions.

Missed Dose

If you miss a dose of Metformin HCL 500 mg tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Overdose

In case of an overdose of Metformin HCL 500 mg tablet, seek immediate medical attention. Overdose symptoms may include severe nausea, vomiting, diarrhea, abdominal pain, difficulty breathing, and dizziness. It is important to follow the recommended dosage and seek medical advice if you have any concerns or questions.

Note: This information is not intended to replace professional medical advice. Please consult your healthcare provider or pharmacist for more information about the dosage and administration of Metformin HCL 500 mg tablet.

Recommended dosage for adults

Initial dose:

The initial recommended dose of Metformin HCL 500 mg tablets for adults is one tablet taken orally once daily with a meal. This initial dose is typically prescribed for individuals who have not previously taken Metformin or who have not achieved glycemic control with other medications. The initial dose can be adjusted based on individual response and blood glucose levels.

Maintenance dose:

After initiating treatment with Metformin HCL 500 mg tablets, the maintenance dose is often individualized based on blood glucose levels. The usual maintenance dose ranges from one to three tablets taken orally once daily with meals. The maximum recommended daily dose is 2000 mg, divided into two to three doses.

Monitoring:

It is important for adults taking Metformin HCL 500 mg tablets to regularly monitor their blood glucose levels to assess the effectiveness of the medication and adjust the dose as needed. In addition, routine monitoring of renal function, including creatinine levels, is recommended to detect any potential adverse effects of the medication.

Special considerations:

It is important to note that the dosage of Metformin HCL 500 mg tablets may need to be adjusted in certain situations. For individuals with impaired renal function, the dose may need to be decreased or the medication may need to be discontinued. Additionally, individuals who are at increased risk for lactic acidosis, such as those with liver disease or alcohol abuse, may require closer monitoring and dose adjustments.

In conclusion, the recommended dosage for adults taking Metformin HCL 500 mg tablets is individualized based on initial response and blood glucose levels. Regular monitoring and adjustments of the dose are important for achieving and maintaining glycemic control. Consult with a healthcare provider for personalized dosing recommendations and to discuss any potential risks or concerns.

How to take Metformin HCL?

Taking Metformin HCL correctly is essential for its effectiveness and to avoid any potential side effects. Here are some important instructions to follow:

1. Follow the prescribed dosage: Your doctor will prescribe the appropriate dosage of Metformin HCL based on your condition. It is important to take the medication exactly as prescribed.
2. Take with meals: Metformin HCL should be taken with meals to help prevent stomach upset. It is generally advised to take it with breakfast and dinner, unless otherwise instructed by your doctor.
3. Do not crush or chew: Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet, as this may alter its effectiveness.
4. Stay hydrated: It is important to drink plenty of fluids while taking Metformin HCL to reduce the risk of dehydration.
5. Monitor blood sugar levels: Regularly monitor your blood sugar levels as directed by your healthcare provider. This will help ensure that the medication is working effectively to control your diabetes.
6. Follow a healthy lifestyle: Taking Metformin HCL is just one part of managing diabetes. It is important to follow a healthy diet, exercise regularly, and maintain a healthy weight to achieve optimal results.
7. Do not skip doses: It is important to take Metformin HCL regularly as prescribed. If you accidentally miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
8. Contact your doctor: If you experience any unusual or severe side effects while taking Metformin HCL, contact your doctor immediately. They will be able to provide guidance and determine the best course of action.

By following these instructions, you can ensure that you are taking Metformin HCL safely and effectively to manage your diabetes. Remember to always consult with your healthcare provider for personalized advice and guidance.

Possible Side Effects

Metformin HCL 500 mg Tablet may cause some side effects. It is important to be aware of these potential side effects and to consult with your doctor if you experience any of them. Common side effects include:

• Nausea and vomiting: Some individuals may experience nausea and vomiting as a result of taking Metformin HCL 500 mg Tablet. If you experience these symptoms, it is recommended to take the medication with food to help alleviate these effects.
• Diarrhea: Metformin HCL 500 mg Tablet can sometimes cause diarrhea. If this occurs, it is important to drink plenty of fluids to prevent dehydration.
• Abdominal discomfort: Some individuals may experience abdominal discomfort, such as cramping or bloating, when taking Metformin HCL 500 mg Tablet. This side effect is usually mild and temporary.
• Headache: Headaches have been reported as a potential side effect of Metformin HCL 500 mg Tablet. If you experience severe or persistent headaches, it is advisable to consult with your doctor.

It is important to note that not everyone will experience these side effects, and some individuals may experience different side effects not listed here. If you have any concerns or questions about the potential side effects of Metformin HCL 500 mg Tablet, it is best to consult with your doctor.

Common side effects of Metformin HCL

Metformin HCL is a medication used to treat type 2 diabetes. While it is generally well tolerated, there are some common side effects that patients may experience. It is important to be aware of these side effects and to contact a healthcare provider if they become severe or persist.

Gastrointestinal side effects

One of the most common side effects of Metformin HCL is gastrointestinal discomfort. This can include symptoms such as nausea, vomiting, diarrhea, and stomach pain. These symptoms usually occur when starting the medication and can improve over time.

Hypoglycemia

Metformin HCL can sometimes cause low blood sugar levels, also known as hypoglycemia. Symptoms of hypoglycemia include weakness, dizziness, sweating, and confusion. It is important for patients taking Metformin HCL to monitor their blood sugar levels regularly and to have a plan in place for treating low blood sugar.

Vitamin B12 deficiency

Long-term use of Metformin HCL can lead to a deficiency in vitamin B12. This can cause symptoms such as fatigue, weakness, and nerve problems. Patients taking Metformin HCL should have their vitamin B12 levels checked regularly and may need to take supplements to prevent deficiency.

• Other possible side effects of Metformin HCL include:
• Headache
• Gas
• Muscle pain
• Heartburn
• Taste changes

It is important to note that these are not all of the possible side effects of Metformin HCL. Patients should consult their healthcare provider for more information and to report any side effects that occur while taking this medication.

Serious side effects to watch for

Lactic acidosis

Lactic acidosis is a serious condition that can occur when there is too much lactic acid in the body. It can cause symptoms such as rapid breathing, a rapid heartbeat, muscle pain or weakness, and dizziness. If you experience any of these symptoms, seek medical attention immediately as lactic acidosis can be life-threatening.

Allergic reactions

Some people may have an allergic reaction to metformin HCL 500 mg tablets. Symptoms of an allergic reaction may include hives, itching, swelling, difficulty breathing, or a rash. If you notice any of these symptoms, stop taking metformin and contact your doctor right away.

Hypoglycemia

Metformin HCL 500 mg tablets can cause low blood sugar levels, also known as hypoglycemia. Signs of hypoglycemia may include shakiness, dizziness, sweating, confusion, and headache. It is important to monitor your blood sugar levels regularly while taking metformin and to speak with your doctor about proper dosage adjustment if you experience symptoms of hypoglycemia.

Gastrointestinal issues

Common side effects of metformin HCL 500 mg tablets include stomach upset, diarrhea, and nausea. However, in some cases, metformin can cause more severe gastrointestinal issues such as abdominal pain, vomiting, or severe diarrhea. If these symptoms persist or become severe, it is important to consult your doctor.

In conclusion, while metformin HCL 500 mg tablets are generally well-tolerated, it is important to be aware of the potential serious side effects. If you experience any of the symptoms mentioned above, seek medical attention promptly. Always consult with your doctor before starting or stopping any medication.

Precautions and Warnings

Talk to Your Doctor

Before taking Metformin HCL 500 mg tablets, it's important to consult with your doctor. They will evaluate your medical history and current medication regimen to determine if Metformin HCL is the right option for you. Your doctor will also consider the potential risks and benefits of taking this medication.

Inform Your Doctor

Make sure to inform your doctor about any previous or existing medical conditions you have. Certain conditions, such as kidney or liver disease, can affect how your body processes Metformin HCL. Additionally, let your doctor know about any allergies you may have, especially to medications or substances that may be found in Metformin HCL tablets.

Monitor Your Blood Sugar Levels

While taking Metformin HCL, it's crucial to regularly monitor your blood sugar levels. This will help you and your doctor keep track of how well the medication is working and adjust your dosage if needed. It's important to follow your doctor's instructions for testing and recording your blood sugar levels accurately.

Avoid Excessive Alcohol Consumption

Excessive alcohol consumption can increase the risk of lactic acidosis when taking Metformin HCL. Therefore, it is advisable to limit or avoid alcohol while using this medication. If you do choose to drink alcohol, discuss it with your doctor to determine if any adjustments to your treatment plan are necessary.

Stay Hydrated

It's important to stay well-hydrated while taking Metformin HCL. Make sure to drink plenty of water and fluids throughout the day. Adequate hydration can help prevent certain side effects of the medication and support overall health and well-being.

Follow a Healthy Lifestyle

Metformin HCL is most effective when combined with a healthy lifestyle. Eating a balanced diet, engaging in regular physical activity, and maintaining a healthy weight can all contribute to better outcomes when using this medication. Your doctor can provide guidance on the specific lifestyle changes that may be beneficial for you.

Remember, always follow your doctor's instructions and report any unusual or severe side effects immediately.

Who should not take Metformin HCL?

1. Individuals with severe kidney disease

If you have severe kidney disease or are on dialysis, it is important to avoid taking Metformin HCL. Metformin is primarily excreted through the kidneys, and if your kidneys are not functioning properly, the drug may build up to toxic levels in your body. Consult your doctor before initiating treatment if you have any kidney problems.

2. Individuals with liver disease

If you have liver disease or a history of liver problems, it is advisable to avoid using Metformin HCL. The drug is metabolized in the liver, and if your liver is not functioning properly, it may affect the way your body processes the medication. It is important to discuss your liver health with your doctor before starting treatment.

3. Individuals with a history of lactic acidosis

If you have a history of lactic acidosis or have experienced this condition in the past, it is not recommended to take Metformin HCL. Lactic acidosis is a rare but serious side effect of Metformin that can be life-threatening. Inform your doctor about any history of lactic acidosis or if you experience symptoms such as muscle pain, difficulty breathing, or stomach discomfort while using the medication.

4. Individuals with certain heart conditions

If you have certain heart conditions, such as congestive heart failure or a recent heart attack, it is important to use caution when taking Metformin HCL. This medication may increase the risk of lactic acidosis in individuals with compromised heart function. Consult your doctor to determine if Metformin HCL is safe for you.

5. Individuals with a hypersensitivity to Metformin

If you have a known hypersensitivity or allergy to Metformin or any of its ingredients, it is important to avoid using Metformin HCL. Seek alternative treatment options and inform your healthcare provider about your allergy before starting any new medications.

Drug interactions to be aware of

1. Blood sugar-lowering medications

If you are taking other medications to lower your blood sugar levels, such as insulin or sulfonylureas, it is important to be mindful of potential drug interactions when taking Metformin HCL 500 mg Tablet. These medications work in different ways to lower blood sugar, and using them together may increase the risk of hypoglycemia (low blood sugar). It is recommended to closely monitor your blood sugar levels and consult with your healthcare provider for proper dosage adjustments.

2. Medications that can cause kidney problems

Metformin is primarily eliminated by the kidneys, so it is essential to avoid the concurrent use of other medications that can potentially cause kidney problems. Certain medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs), some antibiotics, and diuretics, have the potential to affect kidney function. Using these medications alongside metformin may increase the risk of developing lactic acidosis, a serious condition that can lead to organ damage. It is important to talk to your doctor before starting any new medications to ensure their compatibility with metformin.

3. Contrast dye used in medical procedures

If you are scheduled to undergo a medical procedure that involves the use of contrast dye, it is important to inform your healthcare provider about your metformin use. Metformin can increase the risk of developing lactic acidosis when combined with contrast dye, particularly if you have pre-existing kidney problems. Your doctor may advise temporarily discontinuing metformin before the procedure to minimize the risk and ensure your safety.

4. Alcohol

Drinking alcohol while taking Metformin HCL 500 mg Tablet can increase the risk of developing lactic acidosis. Alcohol can impair liver function and affect the clearance of metformin from the body, leading to higher drug levels and potentially serious side effects. It is advisable to limit or avoid alcohol consumption while on metformin therapy to ensure optimal safety and efficacy of the medication.

5. Vitamin B12 supplements

Long-term use of metformin has been associated with a decreased absorption of vitamin B12. If you take metformin for an extended period, it is recommended to discuss with your healthcare provider whether you may benefit from vitamin B12 supplementation. Monitoring B12 levels regularly is essential to prevent deficiency and associated symptoms.

It is crucial to understand and be aware of potential drug interactions when taking Metformin HCL 500 mg Tablet. Open communication with your healthcare provider, regular monitoring of your blood sugar levels, and following the recommended treatment plan will help ensure the safe and effective use of this medication.

 

 

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