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Orlistat 120 mg is a weight loss medication that works by inhibiting the absorption of dietary fat in the body. It belongs to a group of drugs known as lipase inhibitors. When taken with a meal, Orlistat binds to the enzymes in the digestive system that break down fat, preventing them from working properly. This results in the body absorbing less fat from the food consumed, leading to weight loss over time.

Orlistat 120 mg is recommended for individuals who are overweight or obese and are looking to lose weight. It is often used in combination with a reduced-calorie diet and exercise program. The medication is available in capsule form and should be taken orally with water. It is typically taken three times a day, with each main meal that contains fat.

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It is important to follow the instructions provided by your healthcare provider or the product packaging when taking Orlistat 120 mg. The medication should be taken exactly as prescribed, and the recommended dosage should not be exceeded. Generally, it is recommended to take one capsule with each main meal that contains fat, but if a meal is skipped or does not contain fat, the dose can be skipped.

Important note: Orlistat should not be taken within two hours of taking a fat-soluble vitamin supplement, such as vitamins A, D, E, and K. These vitamins are best absorbed with fat, and taking them with Orlistat may reduce their effectiveness.

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Mechanism of Action

1. Inhibition of Lipase Enzyme

Orlistat 120 mg works by inhibiting the action of lipase enzymes in the gastrointestinal tract. Lipase enzymes are responsible for breaking down dietary fats into smaller molecules that can be absorbed by the body. By inhibiting this enzyme, Orlistat prevents the absorption of about 30% of dietary fats, leading to a reduction in calorie intake.

2. Reduction of Fat Absorption

In addition to inhibiting lipase enzymes, Orlistat also reduces the absorption of fat-soluble vitamins, such as vitamin A, D, E, and K. This is because these vitamins rely on dietary fat for absorption. Therefore, it is advisable to take a multivitamin supplement that contains these fat-soluble vitamins while using Orlistat.

3. Increase in Fecal Fat Excretion

Orlistat causes an increase in fecal fat excretion, as the undigested fat passes through the gastrointestinal tract and is eliminated through bowel movements. This leads to weight loss and a decrease in body fat percentage over time.

Overall, the mechanism of action of Orlistat 120 mg helps in reducing calorie intake, inhibiting fat absorption, and increasing fat excretion, thereby aiding in weight loss. It is important to note that Orlistat should be used as part of a comprehensive weight loss program that includes a healthy diet and regular exercise.

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Orlistat works by blocking the absorption of fat in your body. It prevents enzymes in your digestive system from breaking down dietary fats, allowing them to pass through your gut undigested. This helps you consume fewer calories and can lead to significant weight loss.

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This weight loss medication works by blocking the absorption of about one-third of the fat you consume. By reducing the amount of fat absorbed by the body, Orlistat helps to promote weight loss and improve overall health.

Orlistat 120 mg is approved by the FDA and has been available on the market for over 20 years. It is manufactured by reputable pharmaceutical companies, ensuring high-quality and reliable results.

Unlike some other weight loss medications, Orlistat is not a stimulant and does not affect the central nervous system. This makes it a safe option for individuals who are sensitive to stimulants or who have certain medical conditions.

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